[synthesis.]Internal

Regulatory intelligence — not medical or legal advice.

Appearance
Active: dark
Accent
Corner radius
Font
Layout
Data refresh

Runs once per app session in the background and keeps existing data if source APIs are unavailable.

Annotation style
Ask · OpenAI

Requires OPENAI_API_KEY on the server. Heuristics always run first.

← Disease database

multiple endocrine neoplasia type 1

An autosomal dominant tumor predisposition syndrome caused by pathogenic variants in the MEN1 gene, characterized by an increased risk of tumors of the parathyroid glands, pituitary gland, and foregut neuroendocrine tumors (most commonly pancreatic islet cells).

Therapeutic area
Endocrine / Metabolic
Rarity
Unknown
Prevalence
MONDO
MONDO:0007540

Overview

An autosomal dominant tumor predisposition syndrome caused by pathogenic variants in the MEN1 gene, characterized by an increased risk of tumors of the parathyroid glands, pituitary gland, and foregut neuroendocrine tumors (most commonly pancreatic islet cells).

Content last reviewed: 2026-06