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multiple endocrine neoplasia type 2A

An autosomal dominant tumor predisposition disorder caused by pathogenic variants in the RET gene, characterized by an increased risk of medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism.

Therapeutic area: Endocrine / Metabolic
Rarity: Unknown
Prevalence: —
MONDO: MONDO:0008234

Overview

An autosomal dominant tumor predisposition disorder caused by pathogenic variants in the RET gene, characterized by an increased risk of medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism.

Content last reviewed: 2026-06