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← Disease database

obesity due to pro-opiomelanocortin deficiency

Pro-opiomelanocortin (POMC) deficiency is a form of monogenic obesity resulting in severe early-onset obesity, adrenal insufficiency, red hair and pale skin.

Therapeutic area
Endocrine / Metabolic
Rarity
Unknown
Prevalence
—
MONDO
MONDO:0012335

Overview

Pro-opiomelanocortin (POMC) deficiency is a form of monogenic obesity resulting in severe early-onset obesity, adrenal insufficiency, red hair and pale skin.

Content last reviewed: 2026-06