[synthesis.]Internal

Regulatory intelligence — not medical or legal advice.

Appearance
Active: dark
Accent
Corner radius
Font
Layout
Data refresh

Runs once per app session in the background and keeps existing data if source APIs are unavailable.

Annotation style
Ask · OpenAI

Requires OPENAI_API_KEY on the server. Heuristics always run first.

← Disease database

tropical endomyocardial fibrosis

Tropical endomyocardial fibrosis is a restrictive cardiopathy, occurring almost exclusively in children and young adults in tropical and subtropical regions, characterized by endocardial fibrosis, affecting the apices and the inflow tract of the right or left ventricle (or both) and manifesting with a restrictive cardimyopathy and atrioventricular regurgitation leading to severe pulmonary hypertension, very high systemic venous pressure and congestive cardiac failure. Suspected etiologies include helminth and protozoal infestation and malnutrition.

Therapeutic area
Respiratory
Rarity
Unknown
Prevalence
MONDO
MONDO:0019158

Overview

Tropical endomyocardial fibrosis is a restrictive cardiopathy, occurring almost exclusively in children and young adults in tropical and subtropical regions, characterized by endocardial fibrosis, affecting the apices and the inflow tract of the right or left ventricle (or both) and manifesting with a restrictive cardimyopathy and atrioventricular regurgitation leading to severe pulmonary hypertension, very high systemic venous pressure and congestive cardiac failure. Suspected etiologies include helminth and protozoal infestation and malnutrition.

Content last reviewed: 2026-06