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large congenital melanocytic nevus

A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presenting with an elevated risk of malignant transformation.

Therapeutic area: Rare Disease
Rarity: Rare
Prevalence: ~100k patients (est.)
MONDO: MONDO:0044792

Overview

A large, or giant, congenital melanocytic nevus (LCMN or GCMN) is a pigmented skin lesion of more than 20 cm - or 40 cm- respectively, projected adult diameter, composed of melanocytes, and presenting with an elevated risk of malignant transformation.

Content last reviewed: 2026-06